摘要：2015年3月，国际泌尿病理学会（International Society of Urological Pathology，ISUP）在波士顿召开了关于睾丸和阴茎病理相关问题的会议，内容包括来自睾丸大体标本巨检工作组的报告。报告重点介绍了近期发表的有关睾丸肿瘤和腹膜后淋巴结清扫的大体标本处理指南，以及会前对会员进行的在线问卷调查结果总结。调查结果用于启动相关讨论，最终建议由专家讨论决定而非投票产生。会议强调了在大体巨检时对病变评估进而通过显微镜确认的重要性。例如，在许多情况下，只有通过解剖标志指示才可以区分睾丸门部软组织侵犯（pT2）与精索侵犯（pT3），因此需要仔细的大体标本评估才能保证确诊。其他建议是附睾、睾丸网、门部软组织和鞘膜的取材需常规进行，从而确认这些结构是否被侵犯，如果巨检侵犯不确定，则需要镜下进一步排除。最大直径≤2cm的肿瘤必须全部取材包埋。如果肿瘤最大直径>2cm，应取材10块或再按照每厘米额外取材1至2块（以取材块数较多者为准）。
关键词：睾丸，生殖细胞肿瘤，指南
Am J Surg Pathol 2018；42：e33-e43
美国外科病理学杂志中文版2019年第1期全文No.3
陈真伟 翻译 滕晓东 审校
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